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Research Interests
- Bioaerosols
- Environmental microbiology
- Occupational hygiene
- Indoor air quality
- Impact of the built environment
- Environmental hygiene
Current Research
- Emerging infectious disease in British Columbia (Cryptococcus gattii)
- Metabolic products of fungal growth on building materials
- Comparison of field methods for bioaerosol characterization
- Antifungal agents in vivo and in vitro
- Assessing Bioaerosol Exposures to Compost Workers from thermophilic organisms
- Pathogen loading of surface water impacted by agricultural land use
- Microbial removal by slow sand filtration
Bridge Graduate Students
- Bojosi Gamontle PhD student, SOEH
- Calvin Ge, MSc candidate, SOEH
Efficacy of composting to decominate Cryptococcus gattii-infected plant products
Other Graduate Students
- Jack Teng, PhD candidate
BSc (Honours Biology, 2001, McGill University), MSc (Biology, 2004, McGill Unverstity) PhD student Resource Management and Environmental Studies
- Andrea Griffiths
BSc (Biology, 2000 Malaspina), MSc (Occupational and Environmental Hygiene, 2006, UBC), PhD student SOEH
Current Courses Taught
- OCCH 501/SPPH 535 Fundamentals of Occupational and Environmental Hygiene
- OCCH 506 Occupational Hygiene Practice
- BRDG 500 Thesis and Journal Seminar
- PATH548 Directed Studies
- BIOL448 Directed Studies
Other Courses Taught
- OCCH 595 Seminar in Occupational and Environmental Hygiene
Selected
Publications
Publications:
Datta, K, Bartlett, KH, Baer, R, Byrnes, E, Galanis, E, Heitman, J, Hoang, L, Leslie, M, MacDougall, L, Magill, S, Morshed, M, Marr, K. 2009 Cryptococcus gattii: an Emerging Pathogenic Fungus in the Pacific Northwest. Emerging Infectious Diseases 15(8): 1185-1191.
Vanderzwaag, JC, Atwater, JW, Bartlett, KH, Baker, D. 2009 Evaluation of the Long Term Performance and Use of Biosand Filters in Posoltega, Nicaragua. Accepted: Water Quality Research Journal of Canada April 2009
Vanderzwaag, JC, Bartlett, KH, Atwater, JW, Baker, D. 2009 Evaluation of Field Testing Techniques Used in a Household Water Treatment Study in Posoltega, Nicaragua. Accepted: Water Quality Research Journal of Canada November 2008
Datta, K, Bartlett, KH, Marr, KA. 2009 Cryptococcus gattii emergence in Western North America: Exploitation of a Novel Ecological Niche. Interdisciplinary Perspectives on Infectious Diseases v. 2009, Article ID 176532
Hachem, C, Fazio, P, Rao, J, Bartlett, K, Chaubey, YP. 2009 Identification and Transport Investigation of Microbial Volatile Organic Compounds in Full Scale Stud Cavities. Building and Environment 44(8):1691-1698
Maal-Bared, R, Bartlett, KH, Bowie, WR. 2008 Dealing with Waterborne Disease in Canada: Challenges in the Delivery of Safe Drinking Water. Reviews on Environmental health 23(2): 119-133
Rao, J, Fazio, P, Bartlett, KH, Yang, D-Q. 2009 Experimental evaluation of potential movement of airborne mold spores out of stud cavities in full size wall assemblies. Building and Environment 44: 1568-1577
Do, R, Bartlett, KH, Dimich-Ward, H, Chu, W, Kennedy, SM. 2008 Biomarkers of airway acidity and oxidative stress in exhaled breath condensate from grain workers. American Journal of Respiratory and Critical Care Medicine 178:1048-1054
Do, R, Bartlett, KH, Dimich-Ward, h, Chu, W, Kennedy, SM. 2008 Exhaled Breath Condensate Biomarkers of Airway Acidity and Oxidative Stress Among Grain Workers. Respiratory Medicine 102:457-463
Bartlett, KH, Kidd, SE, Kronstad, J. 2007 The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest. Current Fungal Infection Reports 1:108-115.
Nicol, Anne-Marie, Hurrell, Christie, McDowall, Will, Bartlett, Karen, Elmieh, Negar. 2007. Communicating the risks of a new, emerging pathogen: the case of Cryptococcus gattii. Journal of Risk Analysis 28(2): 373-386.
Upton, A, Fraser, JA, Kidd, SE, Bretz, C, Heitman, J, Bartlett, KH, Raverty, S. Marr, KA. 2007 First Contemporary Case of Human Infection with Cryptococcus gattii in Puget Sound: Evidence for Spread of the Vancouver Island Outbreak. Journal of Clinical Microbiology 45(9): 3086-8.
Risovic, V, Rosland, M, Sivak, O, Bartlett, KH, and Wasan, KM. 2007. Assessing the Antifungal Activity of a New, Oral Lipid-Based Amphotericin B Formulation Following Administration to Rats Infected with Aspergillus fumigatus. Drug Development and Industrial Pharmacy, 33: 1-5.
Bartlett, KH, Kidd, SE, Kronstad, J. 2007. The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest. Current Fungal Infection Reports 10(1): 58-65.
Kidd, SE, Chow, Y, Mak, S, Bach, PJ, Chen, H, Hingston, AO, Kronstad, JW, and Bartlett, KH. 2007 Characterization of Environmental Sources of Cryptococcus gattii in British Columbia, Canada, and the Pacific Northwest. Applied and Environmental Microbiology 73 (5):1433 – 1443.
MacDougall, L, Kidd, SE, Galanis, E., Mak, S., Leslie, MJ, Cieslak, PR, Kronstad, JW, Morshed, MG, and Bartlett, KH. 2007. Spread of Cryptococcus gattii from Vancouver Island and its Detection in the Pacific Northwest, USA. Emerg Infect Dis 13(1):42-50.
Kidd, SE, Bach, PJ, Hingston, AO, Mak, S, Chow, Y, MacDougall, L, Kronstad, JW, Bartlett, KH. 2007 Cryptococcus gattii Dispersal Mechanisms, British Columbia, Canada. Emerg Infect Dis 13(1):51-57.
Wasan, KM, Sivak, O, Rosland, M, Bartlett, K. 2006. Assessing the antifungal activity, pharmacokinetics and tissue distribution of amphotericin B following the administration of Abelcet and AmBisome® in combination with caspofungin to rats infected with Aspergillus fumigatus J Pharm Sci 96(7):1737-47.
Astrakianakis, G, Seixas, N, Camp, J, Smith, T, Bartlett, KH, Checkoway, H. 2006. Cotton Dust and Endotoxin Exposure in Three Shanghai Textile Factories; a Comparison of Samplers. J Occup Environ Hyg 3:418-427.
Chun, DTW, Bartlett, KH, Gordon, T, Jacobs, RR, Larsson, B-M, Larsson, L, Lewis, DM, Liesivuori, J, Michel, O, Milton, DK, Rylander, R, Thorne, PS, White, EW, Brown, ME, Gunn, VS, and Würtz, H. 2006. History and results of the two Inter-Laboratory round robin endotoxin assay studies on cotton dust. Am J Ind Med 49(4):301-306.
Becalski, A and Bartlett, KH. 2006. Methanol Exposure to Car Occupants from Windshield Washing Fluid: A Pilot Study. Indoor Air 16: 153-157.
Duncan, C, Stephen, C, Lester, S, Bartlett, KH. 2005. Sub-clinical infection and asymptomatic carriage of Cryptococcus gattii in dogs and cats during an outbreak of cryptococcosis. Medical Mycology 43: 511-516.
Kidd, SE, Guo, H, Bartlett, KH, Kronstad, JW, Xu, J. 2005. Comparative gene genealogies indicate that two clonal lineages of Cryptococcus gattii in British Columbia resemble strains from other geographical areas. Eucaryotic Cell 4: 1629-1638.
Leon, C. Taylor, R., Bartlett, KH, and Wasan, KM. 2005. Effect of Heat-Treatment on Fungizone-Induced Cytotoxicity within Human Kidney Proximal Tubular (HK-2) Cells and Aspergillus fumigatus; the Role of Phopholipases. International Journal of Pharmaceutics 298(1): 211-8.
Duncan C, Stephen C, Lester S and Bartlett, KH. 2005 Follow-up study of dogs and cats with asymptomatic Cryptococcus gattii infection or nasal colonization. Medical Mycology 43: 663-666.
Kidd S, Hagen F, Tscharke M, Huynh M, Bartlett KH, Fyfe, M, MacDougall L, Boekhout T, Kwon-Chung KJ, Meyer W. 2004. A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada). Proceedings of the National Academy of Sciences 101(49): 17258-17263.
Sivak, O., Bartlett, KH., Wasan, K. 2004 Heat-treated Fungizone retains Amphotericin B antifungal activity without renal toxicity in rats infected with Aspergillus fumigatus. Pharmaceutical Research 21(9): 1564-6.
Bartlett, KH., Kennedy, SM., Brauer, M., van Netten, C., Dill, B. 2004 Evaluation and determinants of airborne bacterial concentrations in school classrooms. Journal of Occupational and Environmental Hygiene 1(10):639-647.
Lester, S., Kowalewich, N., Bartlett, KH., Krockenberger, MB., Malik, R. 2004. A clinicopathological evaluation of a cryptococcal outbreak: 38 cases, January 2003 to June 2004. Journal of the American Veterinary Medical Association, 225 (11): 1716-1722.
Sivak, O, Bartlett, K., Risovic, V, Choo, E., Marra, F., Batty, D.S. Jr. , and Wasan, KM. 2004. Assessing the Antifungal Activity and Toxicity Profile of Amphotericin B Lipid Complex (ABLC; Abelcet) in Combination with Caspofungin in Experimental Systemic Aspergillosis. Journal of Pharmaceutical Sciences 93(6):1382-9.
KS Lee, KH Bartlett, M Brauer, GM Stephens, WA Black, K Teschke. 2004.
A field comparison of four samplers for enumerating fungal aerosols I. Sampling Characteristics. Indoor Air 14(5): 360-366.
KS Lee, K Teschke, M Brauer, KH Bartlett. 2004.
A field comparison of four samplers for enumerating fungal aerosols II: Inter-sampler calibrations and caveats. Indoor Air 14(5): 367-72.
KH Bartlett, SM Kennedy, M Brauer, C van Netten, B Dill. 2004. Bioaerosol concentrations in school classrooms: Concentrations and predictors of airborne fungi. Annals of Occupational Hygiene 48(6): 1-8.
SM Kennedy, R Copes, KH Bartlett, M Brauer. 2004. Point of sale glass bottle recycling: indoor airborne exposures and symptoms among employees. Occ Environ Med 61:628-635.
KH Bartlett, PB McCray Jr., PS Thorne. 2004. Reduction in the Bactericidal Activity of Selected Cathelicidin Peptides by Serum or Exogenous Endotoxin. Int J Antimicrob Agents 23(6): 606-612.
KH Bartlett, PB McCray Jr., PS Thorne. 2003. Characterization of Novispirin G10-Induced Lung Toxicity. Antimicrob Agents Chemother 47:3901-3906.
David O'Connell. 2004. "Anti-infectives: A salutory lesson" Nature Reviews Microbiology 2:182 (refers to Antimicrob Agents Chemother 47:3901-3906).
KH Bartlett, E Yau, SC. Hartsel, A Hamer, G Tsai, D Bizzotto and KM Wasan. 2004. Effect of Heat-Treated Amphotericin B on Renal and Fungal Cytotoxicity. Antimicrob Agents Chemother 48:333-336.
KH Bartlett, M Martinez, J Bert. 2004. Modelling of occupant generated CO2 dynamics in naturally ventilated classrooms. Journal of Occupational and Environmental Hygiene 1(3): 139-148.
Relevant reports:
Teng, J, Bartlett, KH, Klinkenberg, B, Morshed, M. Tick-borne zoonoses: proximate and distal determinants of tick-borne zoonoses and the management options to prevent their outbreak and spread. National Collaboration Centre for Environmental Health 2009.
Kodama, D and Bartlett, KH. Literature SDearch to Determine the Gaps in Knowledge of Indoor Air Pollutants. Report prepared for Health Canada May 2009. 63 pages.
Bartlett, KH, Atwater, J, Chow, Y. Assessing Exposures to Compost Workers from Airborne Biohazards. Final Report to WorkSafe BC H06-0088
Buckley, M, Bartlett, K, Bennett, J et al. The Fungal Kingdom, diverse and essential roles in earth's ecosystem. American Academy of Microbiology 2008
Low, D, Bartlett, K, Baudouin, J-L, Bougault, A-M, Brosseau, L, Ericson, P, Gardam, M, Janssen, R, McGeer, A, Briwn-Pallas, L, Stiver, G, Tamblyn, S, Tellier, R. Influenza Transmission and the Role of Personal Protective Equipment: An Assessment of the Evidence. Report prepared for the Public Health Agency of Canada 2007 (58 pages)
Bartlett, KH and Revely, S. Report on the indoor air quality and lighting post occupancy building evaluations of six, Leed-certified buildings. Report prepared for the EcoSmart Foundation November 1, 2006 (30 pages).
Bartlett, KH. Investigation of Occupational Exposures to Forestry Workers from Environmental Cryptococcus neoformans var. gattii. Report to the Workers’ Compensation Board of British Columbia, May 5, 2005.
Ward, H., Bartlett, KH, Kennedy, SM, Chan-Yeung, M. Report on the 2003-2004 Respiratory Health Study of Grain Elevator Workers in the Port of Vancouver. December 22, 2004 (70 pages).
Bartlett, K.H. and Griffiths, A. Health Effects of Exposure to Western Red Cedar (Thuja plicata), Eastern White Cedar (Thuja occidentalis), Redwood (Sequoia sempervirens) and Alaska Yellow Cedar (Chamaecyparis nootkatensis). Report prepared for Forintek Canada Laboratory, January 22, 2004; revised November 18, 2004 (17 pages).
Annalee Yassi, Elizabeth Bryce, David Moore, Robert Janssen, Ray Copes, Karen Bartlett, Mark Fitzgerald ,M. Gilbert, Phil Bigelow, Quinn Danyluk, Bruce Gamage, C. Hon, Thomas Perry, Sharon Saunders, Laurence Svirchev, Ron Thiessen. Protecting the Faces of Health Care Workers: Knowledge Gaps and Research Priorities for Effective Protection against Occupationally-Acquired Respiratory Infectious Diseases. Report prepared for the Change Foundation, Toronto, ON (117 pages) March 31, 2004.
van Netten, C., Bartlett, KH. Report on area sampling for environmental bacteria, fungi and endotoxin at CRD pumping stations. Capital Regional District, Victoria , BC. February 2004.
van Netten, C., Bartlett, KH. Report on personal and area sampling for environmental gases, bacteria, fungi and endotoxin at CRD pumping stations. Capital Regional District, Victoria , BC. March 2003.
KH Bartlett and KS Lee. 2002. A comparison of field methods for the measurement of bioaerosols in public buildings. Final Report to the Workers’ Compensation Board of British Columbia. (Revised July, 2003)
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Karen H. Bartlett
Associate Professor
Graduate Advisor SOEH, Michael Smith Foundation for Health Research Scholar (2002 - 2007)
BSc (1973) University of Victoria, MSc (1994) University of British Columbia [Occupational Hygiene], PhD (2000) University of British Columbia [Interdisciplinary Studies]
School of Environmental Health
Associate Member, Department of Pathology and Laboratory Medicine
Faculty Associate, Institute for Resources, Environment and Sustainability
Associate Member, School of Population and Public Health
College for Interdisciplinary Studies
LPC 364
Tel: 604-822-6019
Fax: 604-822-9588
Lab:
Rm: LPC 346
Tel: 604-822-9573
Fax: 604-822-9588
click here to contact
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